RESUMO
The Highmark Blue Cross/Blue Shield Pegasus Project was created in the fall of 1996 to benchmark best practices at health plans around the United States through extensive interviews, literature searches, and other measures. Characteristics of highly successful health plans across a number of major categories are summarized in the final recommendations presented by this report.
Assuntos
Planos de Seguro Blue Cross Blue Shield/normas , Pesquisa sobre Serviços de Saúde , Gestão da Qualidade Total/classificação , Coleta de Dados , Humanos , Marketing de Serviços de Saúde , Avaliação de Programas e Projetos de Saúde , Gestão da Qualidade Total/normas , Estados UnidosRESUMO
Solid-phase organic synthesis is now a prevalent activity in drug discovery. In keeping with this keen interest is the need to develop reliable automated synthesis instrumentation as well as polymeric supports and linkers suitable for the full range of organic synthesis applications. In this paper, we review our activities in the development of new and enabling tools for automated chemical synthesis, including the following: (i) new solid supports such as ArgoGel (PS-PEG-based) and Argo-X203 (PS-based); and (ii) the Nautilus 2400 system, a fully closed and inert automated chemistry development workstation. Selected chemistry optimization and synthesis examples performed on the Nautilus and new solid supports will be described.
